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Solutions
controlled freeze/thaw
The 4000 Series Controlled Rate Chamber offers uniformity and repeatability in rapid, controlled freezing and thawing applications. Our technology uses forced air circulation to provide efficient pulldown from ambient to the desired temperature. Forced air circulation allows the rapid pulldown process to extend to the fluid core, avoiding false freezing points and optimizing the freezing process (1,000 CFM air circulation).
This unique, convection-based, controlled freezing and thawing process eliminates uncertainty and allows temperature-specific conditioning to satisfy processing and shipping protocols for various pharmaceuticals. Our 4000 Series Controlled Rate Chamber units can meet your freeze/thaw application needs from +40°C to -80°C.
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Model 4000-LC
Applications: Pharmaceutical, BioProcessing
Controls: Programmable LCD
Temp Range: +40°C to -80°C
Storage: 23.3 cu ft / 659.8 l
Electrical:
- 208/240 VAC, 3 Ø, 60Hz, 26 FLA (North America)
- 400 VAC, 3 Ø, 50Hz, 24 FLA (International)
Performance Data:
- Pull Down Empty Chamber in < 1 Hour from +25˚C to -80˚C
- Door Open Recovery @ –80˚C < 10 minutes
- 100L Load +25˚C to –80˚C < 12 Hours
- Uniformity Air Temperature +/- 2.0˚C
- Uniformity Product Temperature +/- 1.0˚C
Refrigeration System:
- Heat Transfer Convection, Air Flow
- High Stage R-449A
- Low Stage R-508B
- Defrost - Auto defrost program
- Heat of Rejection – Air Cooled 38,000 BTU/hr (11 kW/hr)
- Heat of Rejection – Water Cooled 1,700 BTU/hr (0.5 kW/hr)
Model 4000
Applications: Pharmaceutical, BioProcessing
Controls: Fixed Controls
Temp Range: +40°C to -80°C
Storage: 23.3 cu ft / 659.8 l
Electrical:
- 208/240 VAC, 3 Ø, 60Hz, 26 FLA (North America)
- 400 VAC, 3 Ø, 50Hz, 24 FLA (International)
Performance Data:
- Pull Down Empty Chamber in < 1 Hour from +25˚C to -80˚C
- Door Open Recovery @ –80˚C < 10 minutes
- 100L Load +25˚C to –80˚C < 12 Hours
- Uniformity Air Temperature +/- 2.0˚C
- Uniformity Product Temperature +/- 1.0˚C
Refrigeration System:
- Heat Transfer Convection, Air Flow
- High Stage R-449A
- Low Stage R-508B
- Defrost Auto defrost program, EZ1 Key Touch
- Heat of Rejection – Air Cooled 38,000 BTU/hr (11 kW/hr)
- Heat of Rejection – Water Cooled 1,700 BTU/hr (0.5 kW/hr)
4000 Series Controlled Rate Chamber Spare Parts List
Frequently Asked Questions
How often will I need to inspect my 4000 Series Controlled Rate Chamber?
The 4000 Series Controlled Rate Chamber should be inspected monthly dependant on usage.
Does FARRAR offer installation for the 4000 Series Controlled Rate Chamber?
Yes, installation is available for the 4000 Series Controlled Rate Chamber. FARRAR® also offers training and material freezing/thawing load testing for optimal speed and uniformity during operation.
Is the 4000 Series Controlled Rate Freezer similar to a blast freezer?
Yes, the 4000 Series Controlled Rate Chamber is similar to a blast freezer. The major difference between the rate chamber and a blast freezer is the volume of air that is moved through the chamber- 500CFM and the ability to precisely control how fast or slow to freeze the material by modulating the cooling capacity.
Does FARRAR assist with the GMP certification and validation process for the 4000 Series Controlled Rate Chamber?
Yes, our team is able to assist with GMP certification and validation for the 4000 Series Controlled Rate Chamber.
Is the 4000 Series Controlled Rate Freezer similar to a plate freezer?
The 4000 Series Controlled Rate Chamber is designed to freeze both bags and bottles using forced air rather than contact plates like a plate freezer. Customized profiles can be built similar to a plate freezer, however.
What size of bags, bottles, and other storage containers can I place into the 4000 Series Controlled Rate Chamber?
The 4000 series control rate chamber is compatible with nearly any size bag, bottle or other storage containers. Contact us for the ideal freeze/thaw orientation for your application.
What types of bags, bottles, and other storage containers can I place into the 4000 Series Controlled Rate Chamber?
The 4000 Series Controlled Rate Chamber is compatable with any types of bags, bottles or storage containers. For optimal layout within the chamber, contact us.
Does the 4000 Series Controlled Rate Chamber use liquid nitrogen?
No, the 4000 Series Controlled Rate Chamber uses forced air, cascade scroll compressors with 2100W of available cooling capacity.
Does the 4000 Series Controlled Rate Chamber integrate with any remote monitoring or analytics?
Yes, an independent BMS probe can be placed inside the 4000 Series Controlled Rate Chamber to provide monitoring and analytics.
Is the HMI controller on the 4000-LC Controlled Rate Chamber customizable?
The HMI display is available on the 4000-LC Controlled Rate Chamber and is not customizeable, however the controller accommodates customizable freeze/thaw profiles with hold times, and slow or faster rates based on individual needs and preferences.
How long does the freeze process take for the 4000 Series Controlled Rate Chamber?
The length of the freeze process for the 4000 Series Controlled Rate Chamber will vary depending on the volume and chemical composition of the material being frozen in the chamber, and the storage medium shape, insulation level and material. The freeze process for an empty chamber will take about 37 minutes from ambient temperature to -80°C.
How long does the defrost process take for the 4000 Series Controlled Rate Chamber?
The defrost process for the 4000 Series Controlled Rate Chamber takes approximately 5 to 8 minutes.
How does the autodefrost setting on the 4000 Series Controlled Rate Chamber work?
The autodefrost setting for the 4000 Series Controlled Rate Chamber is a manual process; The user will start the defrost process with a push button at the end of each of each freeze process.
What is the temperature range for the 4000 Series Controlled Rate Chamber?
The 4000 Series Controlled Rate Chamber supports +40°C (highest during thaw cycle) to -80°C (lowest freeze temp).
What types of life science applications does the 4000 Series Controlled Rate Chamber support?
FARRAR's 4000 Series Controlled Rate Chamber supports bioprocessing, biomanufacturing, drug substance and drug product applications.
Does the Controlled Rate Chamber integrate with any remote monitoring or analytics?
The 4000 Series Controlled Rate Chamber does not currently integrate with any remote monitoring or analytics.
What is the warranty for the 4000 Series Controlled Rate Chamber?
The 4000 Series Controlled Rate Chamber has a 1-year standard (parts and labor) warranty in North America which is extendable for an additional two years. Globally, we offer a 1 year, parts only warranty that is also extendable for an additional 2 years.
Low-Temperature Spaces
Within life sciences, we’re driven to provide customers with proven, engineered, integrated, controlled-environment solutions including bulk storage, blast-freezing, production freezers, and cold spaces (+40°C to -80°C) for product and process development facilities. This includes:
Stability Rooms | +13°C to +40°C
Finished Goods Storage | +1°C to +12°C, with a +5°C=set point
Bulk Product Unfinished Goods | -20°C
Biologic Material Storage | -30°C to -40°C
Vaccine and Drug Substance Storage | -50°C to -80°C
FARRAR® EcoFlex
The FARRAR® EcoFlex is a top-mount, walk-in, modular environmental chamber – an industry game-changer – for anyone seeking a sole-sourced, critically classified solution. This value-engineered chamber is ideal for pharmaceutical/biopharmaceutical manufacturing, healthcare systems, research labs, universities and more.
With a temperature range of +4°C to +37°C and an energy efficient variable speed evaporator and compressor, EcoFlex offers temperature uniformity, quiet/ compact operation and a refrigeration system that is factory-acceptance tested, charged, and operational before arrival.
- Prepackaged, modular approach eliminates field refrigeration piping
- Unique design provides 100% usable volume within the room
- Service/maintenance completed externally so valuable product is untouched and undisturbed
- Designed with sustainability in mind
- Temperature flexibility from +4°C to +37°C
- Very small refrigerant charge using Low-GWP R-448A
- Up to 50% energy savings over traditional systems*
Reduced compressor load to promote longer lifecycle value
- Pharma/Biopharma Manufacturing
- Healthcare Systems
- Research Labs
- Academia/Research
- Life Sciences
Modular approach enables the equipment to be redeployed after room modifications or relocation.
Optional fully coated cooling coils for anti-corrosion and maximum lifecycle.
Modular prepackaged FAT cooling heating unit with variable speed evaporator fans and a variable speed compressor resulting in up to 50% energy savings over traditional system designs.*
Very small refrigerant charge using R-448A. This ensures clients have a future proofed system that only requires a 6 lb. charge of refrigerant. This eliminates the need for a larger refrigerant charge and potential leak risk.
Quiet and compact refrigeration system is factory-acceptance tested, charged, and operational before arrival.
All units are assembled in North America with quick-ship replacement parts available.
Frequently Asked Questions
Is the EcoFlex a LEED driven design?
Yes. FARRAR’s EcoFlex uses low GWP R-448 refrigerant which results in up to 50% lower energy consumption. The design helps ensure customers have a future-proofed system that only requires a 6-pound charge of refrigerant. This eliminates the need for a larger refrigerant charge and potential leak risk.
*Up to 50 percent more energy efficient in standard use vs. traditional environmental rooms, dependent on loading
Once constructed, can the FARRAR EcoFlex be relocated?
The modular construction of the EcoFlex enables the equipment to be redeployed after room modifications or relocation.
At what temperature range does the FARRAR EcoFlex operate?
The EcoFlex has a simple setpoint that allows the standard unit to operate in a full range of +4°C up to +37°C with precision control (+/- 0.5°C).
What is the EcoFlex?
FARRAR® EcoFlex is an eco-friendly environmental chamber with precision-controlled temperature and humidity.
What support can I expect from FARRAR on a walk-in project?
In addition to end-to-end planning and installation capabilities (engineering and project management), FARRAR provides calibrations, turnkey installation and start-up, training and technical support and validation services. After installation, FARRAR offers scalable nationwide maintenance and calibration plans, remote preventative and predictive monitoring, and proactive technical response.
What types of walk-in rooms can FARRAR engineer?
Leveraging deep-application expertise, our team engineers walk-in environmental chambers for ultra-low temperature suites, freezers, and cold, warm, cold clean, stability (temperature and humidity), and wide-range rooms.
What types of life science materials and drug products are stored in FARRAR’s engineered walk-in rooms?
Our engineered solutions are ideal for companies committed to mission-critical refrigeration processes and storage. FARRAR chambers adhere to tight environmental specifications to help protect finished goods, bulk unfinished goods, frozen biologic material, as well as vaccine and drug substances.
Does FARRAR use low GWP refrigerants?
FARRAR does use low GWP refrigerants in our Walk-In spaces. The Ultra-Low Chamber (ULC) Series and 4000 Series Controlled Rate Chamber use the lowest GWP refrigerants available in the charge levels needed to provide enough cooling capacity to the chamber. Global refrigerant charge limitations on flammable refrigerants such as hydrocarbons limit our ULC and Rate chamber GWP listings. However, Trane Technologies and FARRAR have a dedicated refrigerant design team investigating new formulas that significantly lower GWP without impacting charge limitation rules.
What are the available temperature ranges for walk-in freezer?
FARRAR provides Walk-In freezers and cold rooms from +40°C to -80°C.
What do I need to provide to get a quote for walk-in freezer?
Our trained team can guide you to choose the best solution for your application. You do not have to know everything about your refrigeration needs, however, knowing your intended storage temperature range, desired volume and amount of entries per day into the space are a great start to a painless design process.
Engineered Cold Room Solutions
FARRAR’s Engineered Solutions leverage deep application expertise and a broad range of refrigerants, equipment, material handling, access, and enclosures to develop the right solution for each product and process in a variety of life science applications.
Frequently Asked Questions
Does FARRAR build walk-in Stability Chambers/Rooms?
Yes, FARRAR provides Stability Chambers/Rooms with a temperature range of +13°C to + 40°C.
What are the available temperature ranges for walk-in rooms?
FARRAR’s walk-in environmental chambers have a temperature range of +40°C to -80°C.
What types of walk-in cold rooms can FARRAR build?
FARRAR builds a variety of walk-in environmental chambers including Stability Rooms (+13°C to +55°C), Finished Goods Storage (+1°C to +12°C), Bulk Product Unfinished Goods Storage (-20°C), Frozen Biologic Material Storage (-30°C to -40°C), and Vaccine and Drug Substance Storage (-50°C to -80°C).
What is the approximate lead time required for construction of a FARRAR walk-in cold room?
While dependent on the size and scope of the project, on average the total lead time from initiation to final set up and installation is between 16 and 20 weeks.
Do you engineer, build, and validate your walk-in spaces?
Yes, FARRAR offers end-to-end planning and installation capabilities including validation services such as IQ/OQ and PQ.
Does FARRAR install and service walk-in chambers across the United States?
Yes, FARRAR installs and services precision-climate walk-in chambers for laboratory, biobanking, biopharma, clinical storage, and other applications across the United States.
Does FARRAR provide a Service and Maintenance Contract for walk-in chambers?
Yes, FARRAR offers Service and Maintenance Contracts for our walk-in chambers as part of the base proposal or after the sale occurs.
What support can I expect from FARRAR on a walk-in project?
In addition to end-to-end planning and installation capabilities (engineering and project management), FARRAR provides calibrations, turnkey installation and start-up, training and technical support and validation services. After installation, FARRAR offers scalable nationwide maintenance and calibration plans, remote preventative and predictive monitoring, and proactive technical response.
What types of walk-in rooms can FARRAR engineer?
Leveraging deep-application expertise, our team engineers walk-in environmental chambers for ultra-low temperature suites, freezers, and cold, warm, cold clean, stability (temperature and humidity), and wide-range rooms.
What types of life science materials and drug products are stored in FARRAR’s engineered walk-in rooms?
Our engineered solutions are ideal for companies committed to mission-critical refrigeration processes and storage. FARRAR chambers adhere to tight environmental specifications to help protect finished goods, bulk unfinished goods, frozen biologic material, as well as vaccine and drug substances.
Does FARRAR use low GWP refrigerants?
FARRAR does use low GWP refrigerants in our Walk-In spaces. The Ultra-Low Chamber (ULC) Series and 4000 Series Controlled Rate Chamber use the lowest GWP refrigerants available in the charge levels needed to provide enough cooling capacity to the chamber. Global refrigerant charge limitations on flammable refrigerants such as hydrocarbons limit our ULC and Rate chamber GWP listings. However, Trane Technologies and FARRAR have a dedicated refrigerant design team investigating new formulas that significantly lower GWP without impacting charge limitation rules.
What are the available temperature ranges for walk-in freezer?
FARRAR provides Walk-In freezers and cold rooms from +40°C to -80°C.
What do I need to provide to get a quote for walk-in freezer?
Our trained team can guide you to choose the best solution for your application. You do not have to know everything about your refrigeration needs, however, knowing your intended storage temperature range, desired volume and amount of entries per day into the space are a great start to a painless design process.
overview
Efficient process flow requires safe and reliable product transfer equipment. To help maintain product integrity and help ensure material handling safety and efficiency, FARRAR offers standard and custom material handling systems for manufacturing process needs.
These portable carts specifically designed for the ULC-190 and ULC-328 units accommodate all types and sizes of product containers.
Need help identifying the right system? Don’t see what you are looking for? Consult with FARRAR for a custom solution to optimize your process and improve productivity.
Product Cart for Ultra-Low Chamber (ULC-190)
- Bottle Capacity: 36 x 10 L Bottles
- Cart Capacity: 1100 lb
- Shelf Capacity: 275 lb
- Integrated Center Guide and Cane Pin Latch
- Corrosion-Resistant Swivel Locking Casters
- 4 in Phenolic Wheels
- Weight Empty ≈ 200 lb
- Pairs with ULC Transfer Cart
Product Cart for Ultra-Low Chamber-Pallet (ULC-328)
- Bottle Capacity: 32 x 10 L Bottles
- Cart Capacity: 1100 lb
- Shelf Capacity: 245 lb
- Integrated Center Guide and Cane Pin Latch
- Corrosion-Resistant Swivel Locking Casters
- 4 in Phenolic Wheels
- Weight Empty ≈ 250 lb
Transfer Cart for Ultra-Low Chamber (ULC-190)
- Cart Capacity: 1300 lb
- Integrated Cane Pin for Concrete Holes
- Corrosion-Resistant Swivel Locking Casters
- 4 in Phenolic Wheels
- Weight Empty ≈ 175 lb
- Pairs with Product Bottle Cart for Ultra-Low Chamber
Transfer Cart for Ultra-Low Chamber-Pallet (ULC-328)
- Cart Capacity 1350 lb
- Integrated Cane Pin for Concrete Holes
- Corrosion-Resistant Swivel Locking Casters
- 4 in Phenolic Wheels
- Weight Empty≈250 lb
Frequently Asked Questions
What types of additional storage tools or material handling does FARRAR provide?
FARRAR® provides standard and custom material handling systems for bulk materials, finished goods and small samples, including product and transfer carts for the Ultra-Low Chamber (ULC) Series.