Resources

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Innovations in Freezer Technology that Help Protect Sample Integrity
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Innovations in Freezer Technology that Help Protect Sample Integrity

As a pharma professional working in the GMP environment, you understand the critical importance of maintaining sample integrity, optimizing workflow, and conserving energy. Join us for our webinar on the latest advancements in cold storage technology for the pharmaceutical industry and discover how to stay ahead of the curve. Over the past decade, the demand for -60°C through -80°C assets in pharmaceutical manufacturing has skyrocketed. Clinical research investments have expanded, and commercial-scale needs continue transforming the industry. However, the lack of alternative solutions has made cold wall technology the gold standard.

But here’s the catch – cold-wall technologies were not designed or intended to perform in certain applications that are becoming increasingly common. Factors such as expedited commercialization of drug products, the need for bulk volumes, and the demand for flexible temperature setpoints have stressed traditional cold-wall systems.

Is there an alternative technology that can address these challenges? The answer is a resounding “yes.” Join us for this webinar to explore forced-air convection technology and discover how it can revolutionize your operations.

Watch this webinar on-demand to explore forced-air convection technology and discover how it can revolutionize your operations.

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Advanced Blast Freezing Technologies for Drug Product Development
On-Demand Webinar
Advanced Blast Freezing Technologies for Drug Product Development

Balancing performance and cost is an ongoing challenge for the biopharmaceutical industry. When this is compounded by additional factors - including the scaling of complex therapeutics, global supply chain challenges, product loss, and more - it can greatly impact the ability to achieve the best return on investment and greatest process optimization.

While the challenges are complex, it is possible to attain optimal performance, operational excellence, and cost-effectiveness when the right tools are in place, supporting the development and validation of a robust freeze/thaw process that meets regulatory guidelines.

Join Entegris and FARRAR to discuss freeze/thaw technology advancements in drug product development that can help support operational excellence.

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Uniformity, Flexibility, Reliability: Achieve it All with FARRAR EcoFlex
On-Demand
Uniformity, Flexibility, Reliability: Achieve it All with FARRAR EcoFlex

Biopharmaceutical manufacturers, CDMOs, and other life science businesses are challenged when it comes to maintaining sample viability, temperature uniformity, reliability of equipment, and application flexibility. The expectation of energy efficiency and adherence to sustainable best practices combined with these performance requirements can make equipment selection difficult and time-consuming.

The FARRARTM EcoFlex walk-in environmental chamber is ideal for those seeking a solution that checks all the boxes. With a +4°C to +37°C temperature range, built-in backup system, precise temperature and humidity control, and ease of maintenance, EcoFlex is ideal for stability testing applications.

Check out this informative discussion to learn more about the FARRAR EcoFlex walk-in environmental chamber that helps support operations and sustainability goals for both you and your customers.

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Safeguarding Performance and Sample Integrity: Solutions to Achieve Flexibility in Freezing and Storage Applications
On-Demand
Safeguarding Performance and Sample Integrity: Solutions to Achieve Flexibility in Freezing and Storage Applications

The need for -60°C through -80°C assets to help future-proof manufacturing facilities has increased significantly over the past decade - clinical research investments have expanded while commercial-scale needs continue to transform the landscape.

Cold wall remains the gold standard due to a lack of alternative solutions. Several factors, however, have placed stress on cold-wall technologies to perform in applications for which they were not designed or intended. These include:

  • the expedited commercialization of drug product/drug substances,
  • the need for bulk volumes, and
  • increased demand for flexible temperature setpoints.

Does an alternative technology exist? The short answer is “yes.” Join us to learn more about FARRAR’s wide range of convection-cooling solutions, providing the performance and reliability you need.

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Unlock the Gridlock in Your Bio-logistics Workflow: Meet the ULC-259
On-Demand
Unlock the Gridlock in Your Bio-logistics Workflow: Meet the ULC-259

The demand for freezing and cold storage solutions that provide maximum density, flexibility, and material handling that optimizes workflow and process is critical.

To help meet the needs of biopharmaceutical manufacturing, bio-logistics and clinical trial customers, FARRAR™ is excited to announce a new offering in our -20°C to -80°C ultra-cold chamber reach-in series – the ULC-259!

  • Is your current ULT freezer a limiting factor/bottleneck in production?
  • Do you spend too much time taking freezers out of service for manual defrost maintenance, adding complexity to your process?
  • Does limiting access to your freezers to allow them to recover from door opening inhibit your operations?
  • Do you consider your material loading and unloading from your cold storage equipment inefficient because it is a product of the equipment you have?

The new ULC-259 offers the performance customers have come to rely on and more from our ULC family of fully redundant, forced air convection style freezers.

Webinar attendees will walk away with insights on:

  • Bioprocessing industry trends: Growing demand for wide range but precise, temperature drug substance/drug product storage
  • Advanced freezer technology: Impact of forced air convection on uniformity in wide temperature applications
  • ULT wide temperature design limitations: Challenges current ULT engineering faces
  • Material handling innovations that streamline workflow processes

This webinar is ideal for individuals involved in:

Biopharmaceutical Manufacturing

Biobanking and Biorepositories

Clinical Trial Kitting

Bulk Drug Substance Manufacturing

CMO/CDMO

Cold Chain Logistics

Filled and Finished Biologic Drug Storage and Logistics

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Righting the Wrongs in Walk-in Cold Room Equipment Sizing
On-Demand
Righting the Wrongs in Walk-in Cold Room Equipment Sizing

With drug manufacturing moving at an unprecedented speed, pharma and biopharma industry facility managers are struggling to align standard requirements with needs for walk-in cold chamber bulk storage construction. Deep knowledge of customer workflow and processes is critical to success.

  • How do you help customers determine what they need?
  • Are you challenged with vague or predetermined specs from RFPs?
  • Is your goal to incorporate alternative system designs to improve sustainability?

Make sure you're up to speed on the latest industry information about the complexities of designing for low-temperature walk-in cold rooms.

Webinar attendees will walk away with insights on:

  • Walk-in Cold Room Decision Criteria
  • Managing Spec Constraints
  • Facility Impact
  • Refrigerant Considerations

Ideal attendees include:

  • Facilities Managers
  • Consulting Engineers
  • Bioprocess Engineers
  • Procurement Leaders
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Reliable Ultra-Cold Storage Chambers: Path to Speedy Temperature Recovery from Door Openings
On-Demand
Reliable Ultra-Cold Storage Chambers: Path to Speedy Temperature Recovery from Door Openings

With drug manufacturing moving at an unprecedented speed, pharma and bio-pharma industry experts are rethinking bulk cold storage overall. Should you be as well?

• Are you challenged by poor temperature recovery from door openings?
• Do you routinely put warm drug product in freezers?
• Do you maintain empty backup freezers in case a chamber goes down?

Make sure you're up to speed on the latest industry information about the complexities of ultra-cold storage — and the latest offerings to optimize your process.

Webinar attendees will walk away with insights on:
• How to ensure temperature uniformity and fast temperature recovery
• Ways to conserve footprint while increasing yield
• A strategy for alleviating empty backup freezers

Ideal attendees include:
• Bioprocess Engineers
• Director of Operations
• Director of Manufacturing
• Procurement Leaders
• Facilities Managers

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Burned Out from Burning Out -80° ULT Freezers
On-Demand
Burned Out from Burning Out -80° ULT Freezers

During this webinar you’ll learn more about:

  • The pros and cons of existing freezer technology versus alternative cooling technology
  • What leads to ultra-low temperature (ULT) equipment failure in critical temperature environments
  • How to identify the right freezer equipment for the right application
  • Real-life examples of how new freezer technology can improve ROI
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White Papers & Case Studies

Farrar | Trane Technologies Help Plasma Collection Industry Leader Expand Nationwide Footprint
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FARRAR's Predictive Analytics Help Eliminate $300MM in annual drug loss
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FARRAR + Gram Collaboration Yields Fast Turn, Smaller Footprint and Precise Control
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4000 Series Controlled Rate Chamber: Innovative Freezer Technology Revolutionizes Biologic Drug Handling
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ASI Acclimate Freeze Rates in Farrar Scientific’s Model 4002 Rate Chamber
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Effect of Controlled Rate Freeze and Thaw on Biopharmaceuticals
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Freezing Rate Controlled Validation
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Bag Freezing and Thawing Rate Controlled Validation 16-L Bag Study
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Third-Party Studies

BioProcess International: Validation of Controlled Freezing and Thawing: A 9-L Bottle Study
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BioProcess International: Validation of Controlled Freezing and Thawing Rates: A 16-L–Bag Study
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SPEC Sheets

4000 Air-Cooled Spec Sheet
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4000 Water-Cooled Spec Sheet
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4000-LC Air-Cooled Spec Sheet
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4000-LC Water-Cooled Spec Sheet
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ULC-259 Water-Cooled Spec Sheet
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ULC-259 Air-Cooled Spec Sheet
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ULC-311 Water-Cooled Spec Sheet
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ULC-311 Air-Cooled Spec Sheet
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ULC-190 Water-Cooled Spec Sheet
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ULC-190 Air-Cooled Spec Sheet
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Technical Data SHEETS

Technical Data Sheet - Model 4000
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Technical Data Sheet - Model 4000LC
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Technical Data Sheet: Ultra-Low Chamber Series
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Technical Data Sheet - Model 4000 (DE)
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Technical Data Sheet - Model 4000LC (DE)
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FARRAR™ EcoFlex Data Sheet
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FLF105 Undercounter Technical Data Sheet
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FLF120 Upright Technical Data Sheet
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FLF125 Upright Technical Data Sheet
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FLR105 Undercounter Technical Data Sheet
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FLR245 Upright Technical Data Sheet
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FUF126 ULT Technical Data Sheet
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FLR125 Upright Technical Data Sheet
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FLR120 Upright Technical Data Sheet
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TEST Data

Thaw Test
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This test data is an example of rigid containers during a control rate thaw process from -80°C to +6°C (+/-2°C). The sample rate for data gathered was every ten seconds for a period of 30 hours. (Phase change -0.5 +/-1)
Pull-Down Tests of Various Rigid Container Profiles
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This test data is an example of control rate freezing from +24°C to -79°C in rigid containers. The freeze time for +24°C to -79°C was 15.5 hours. (Phase change -0.5 +/-1)
Product Phase Change -36C
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This test data is an example of ambient down to -85°C using simulated product freezing at -30°C. (Phase change -30 +/-2)
100 Bottle Pull Down Test
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This test data is an example of control rate freezing from ambient down to -80°C using 100 rigid containers. -80°C achieved in 13.07 hours. (Phase change -0.5 +/-1)
-50C Stability Test Empty Chamber Mapping
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Test data is an example of the temperature uniformity of a ULC-190 with a temperature set point of -50°C using 5 sensors per plane located at the top, middle and bottom shelves in the chamber. TCs 16 and 17 are control sensor and ambient, respectively. Uniformity data is captured in 5 minute intervals over a 42 hour period. The temperature uniformity over the period is +/-3.1°C. Sensors are in open air; not weighted
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Five Key Cold Storage Selection Questions eBook